Research Grade Glofitamab

CAT: 1358-HY257146-01Size: 100 µgDry Ice: NoHazardous: No
CAT#:1358-HY257146-01Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GlofitamabisaT-cell-engagingbispecificantibodypossessinganovel2:1structurewithbivalencyforCD20onBcellsandmonovalencyforCD3onTcells.Glofitamabisaninvestigational, T-cellbispecificantibodywithadistinctivedesignthatfeatures2FabarmsforbindingCD20onBcells, alongwith1FabarmforbindingCD3onTcells.TheCD3bindingarmisfuseddirectlytooneoftheCD20-bindingarmsinahead-to-tailfashionviaashortflexiblelinker.
Product Name Alternative
Bispecific, CD20-TCB (2:1), RG-6026, CAS:2229047-91-8
Expression System
Mammalian Cells
Host
Humanized
Target
B-lymphocytesurfaceantigenB1, Membrane-spanning4-domainssubfamilyAmember1, MS4A1, LeukocytesurfaceantigenLeu-16, B-lymphocyteantigenCD20, Bp35, CD20, T3E, T-cellsurfaceantigenT3/Leu-4epsilonchain, CD3e, CD3E, T-cellsurfaceglycoproteinCD3epsilonchain
Clonality
Monoclonal
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Purification
Protein A/G purified from cell culture supernatant.
Concentration
1.06mg/ml
Endotoxin
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Form
Liquid
Buffer
0.01M PBS, pH7.4.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at4°C short term (1-2weeks) . Store at-20°C 12 months. Store at -176°C long term.
Notes
For research use only. Not suitable for clinical or therapeutic use.
Buffer pH
0.01M PBS, pH7.4.
Species
Human
Isotype
IgG1-kappa-lambda

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