Resistin

CAT: 1324-E50Size: 96 TestsDry Ice: NoHazardous: No
CAT#:1324-E50Size:96 Tests
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Description
Resistin (FIZZ3) is a hormone influencing fat metabolism and inflammation processes. In humans, it is expressed in bone marrow and transported by macrophages into adipose tissue. Resistin stimulates pre-adipocyte proliferation and lipolysis of mature adipocytes probably by influencing MAPK signaling. With regard to the importance of Resistin in disorders of energy metabolism, a significant reduction could be shown in patients with anorexia nervosa. It has been demonstrated that Resistin enhances the expression of specific cell markers such as VACM-1 and ICAM-1 and thus may influence endothelial inflammatory processes, and thereby arteriosclerosis. Moreover, due to its association with Endothelin-1, Resistin also plays a role in cardiovascular diseases. Resistin is relevant to medical conditions such as: • Obesity • Insulin resistance, diabetes • Arteriosclerosis • Inflammation • Lipolysis
Assay Type
ELISA
Sample Volume
15 µL (dilute 1:21; recommended)
Detection Range
20 – 1000 pg/mL
Sensitivity
12 pg/mL
Species
Human
Incubation Time
4 Hours

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