Anti C4d

CAT: 1324-BI-RC4DSize: 96 TestsDry Ice: NoHazardous: No

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CAT#:1324-BI-RC4DSize:96 Tests

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

The antibody has been tested for use on paraffin sections and frozen sections of human tissue. Working protocol available. Recommended dilution for immunohistochemistry: 1:30 – 1:50 Pretreatment of slides by pressure cooking (5 minutes at +125°C in TRIS/EDTA buffer pH 8.5) is highly recommended for antigen retrieval. Intended use: C4d is the degradation product of the activated complement factor C4, a component of the classical complement cascade, which is typically initiated by binding of antibodies to specific target molecules. Detection of C4d is regarded as an indirect sign, a "footprint" of an antibody response against the allograft. The majority of publications describe C4d as an important biomarker in kidney transplantation but also in heart, liver, and other transplants. Intended applications: Humoral transplant rejection

Assay Type

Immunohistochemistry

Sample Volume

250 μL

Species

Human

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Anti C4d

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