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Recombinant Human GRO Protein

CAT: 0763-PDEH100728-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0763-PDEH100728-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha (4-73), GRO-alpha (5-73) and GRO-alpha (6-73) show a 30-fold higher chemotactic activity.
Abbreviation
GRO
Synonyms
C-X-C motif chemokine 1; CXCL1; GRO-alpha (1-73) ; GRO1; GROA; Growth-regulated alpha protein; MGSA; Melanoma growth stimulatory activity; NAP-3; Neutrophil-activating protein 3; SCYB1
UniProt
P09341
Accession Number
P09341
Expression System
E.coli
Tag
N-His
Sequence
Ala35-Asn107
Field of Research
Cancer; Cardiovascular; Immunology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
10.2 kDa
Observed Molecular Weight
11 kDa
Species
Human

UniProtKB · P09341

Growth-regulated alpha protein

GROA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09341
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CXCL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q9UCR7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

CytokineGrowth factor

PTM

Disulfide bond

Biological process

Inflammatory response

Cellular component

Secreted

Domain

Signal
Product Datasheet
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