Recombinant IL-5 Monoclonal Antibody

• Background:

  This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF) . This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

• Abbreviation:

  IL5

• UniProt:

  P05113

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human IL-5 Protein

• Target:

  Nterleukin; Interleukin; IL5; EDF; IL-5; TRF; BCDFII; B-cell differentiation factor I; B-cell growth factor I; BCGF-II; Cytotoxic T-lymphocyte inducer; E-CSF; Eosinophil differentiation factor; ESGF; Interleukin-5; nterleukin-5; T-cell replacing factor

• Clonality:

  Monoclonal

• Clone:

  10C8

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Immunology; Cancer

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  15 kDa

• Observed Molecular Weight:

  20 kDa

• Isotype:

  IgG