Recombinant GSTM2 Monoclonal Antibody

• Background:

  Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

• Abbreviation:

  GSTM2

• UniProt:

  P28161

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human GSTM2 protein

• Target:

  GST; GSTM2; GST4; GSTM; GSTM2-2; GTHMUS; Glutathione S alkyltransferase M2; Glutathione S aralkyltransferase M2; Glutathione S aryltransferase M2; Glutathione S transferase 4; Glutathione S transferase M1; Glutathione S transferase M2 (muscle) ; Glutathione S transferase Mu 2; Glutathione S transferase Mu 2 (muscle) ; glutathione S-transferase mu 2; glutathione S-transferase mu 2 (muscle) ; GST class mu 2; GST class-mu 2; GST muscle; MGC117303; S (hydroxyalkyl) glutathione lyase M2

• Clonality:

  Monoclonal

• Clone:

  6F5

• Conjugation:

  Unconjugated

• Applications:

  IHC-P

• Field of Research:

  Signal Transduction; Metabolism; Tags & Cell Markers

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  IHC-P 1:100-1:500

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Isotype:

  IgG