Recombinant Leptin/LEP Monoclonal Antibody

• Background:

  Leptin is a protein product of the mouse obese gene. Mice with mutations in the obese gene that block the sythesis of Leptin have been found to be obese, diabetic and to have reduced activity, metabolism and body temperature. cDNA clones encoding Leptin have been isolated from human, simian, mouse and rat cells. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin cDNA encodes a 167 amino acid residue protein with a 21 amino acid residue signal sequence that is cleaved to yield the 146 amino acid residue mature protein. The expression of Leptin mRNA has been shown to be restricted to adipose tissue.

• Abbreviation:

  LEP

• UniProt:

  P41159

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Leptin / LEP Protein

• Target:

  LEP; LEPD; OB; OBS; leptin; Obesity Homolog; Obese protein; Obesity factor; FLJ94114; homolog of; Leptin (murine obesity homolog) ; Leptin (obesity homolog; Leptin Murine Obesity Homolog; Leptin Precursor Obesity Factor; mouse; mouse) ; Obese; Obesity; Obesity homolog mouse; Obesity Murine Homolog Leptin; OTTHUMP00000212285

• Clonality:

  Monoclonal

• Clone:

  9B10

• Conjugation:

  Unconjugated

• Applications:

  FCM; ICC/IF

• Field of Research:

  Signal Transduction; Neuroscience; Stem Cells; Cardiovascular; Metabolism

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  ICC/IF 1:20-1:100; FCM 1:25-1:100

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Isotype:

  IgG