Recombinant CD171/N-CAML1/L1CAM Monoclonal Antibody

• Background:

  The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus) . Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

• Abbreviation:

  L1CAM

• UniProt:

  P32004

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human CD171 / N-CAML1 / L1CAM protein

• Target:

  MIC; SPG; CAML; N-CAML; NCAM-L; N-CAM-L; L1CAM; CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1; N-CAM L1; L1 antigen; CAML1; CD171; HSAS; HSAS1; L1cam; MASA; MIC5; S10; SPG1; Antigen identified by monoclonal antibody R1; Antigen identified by monoclonal R1; CD171 antigen; Hyd; L1 cell adhesion molecule; L1-NCAM; N CAML1; NCAML1; Nerve-growth factor-inducible large external glycoprotein; Neural cell adhesion molecule L1; NILE; OTTHUMP00000025992

• Clonality:

  Monoclonal

• Clone:

  8B9

• Conjugation:

  Unconjugated

• Applications:

  IHC-P; FCM; ICC/IF

• Field of Research:

  Signal Transduction; Neuroscience

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  IHC-P 1:100-1:500; ICC/IF 1:20-1:100; FCM 1:25-1:100

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Isotype:

  IgG