Recombinant ALK-1/ACVRL1 Monoclonal Antibody

• Background:

  This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

• Abbreviation:

  ACVRL1

• UniProt:

  P37023

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human ALK-1 / ACVRL1 protein

• Target:

  SKR; ORW; Activin Receptor-Like Kinase; Serine/Threonine-Protein Kinase Receptor R; ACVRL; ACVRLK; ALK; ACVRL1; ACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3; TSR-I; Activin Receptor-Like Kinase 1; Serine/Threonine-Protein Kinase Receptor R3; TGF-B Superfamily Receptor Type I

• Clonality:

  Monoclonal

• Clone:

  7B6

• Conjugation:

  Unconjugated

• Applications:

  WB; IP

• Field of Research:

  Cardiovascular; Signal Transduction; Metabolism

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000; IP 1-4 μL/mg of lysate

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  56 kDa

• Observed Molecular Weight:

  41 kDa

• Isotype:

  IgG