Recombinant Sox2 Monoclonal Antibody

• Background:

  This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) .

• Abbreviation:

  Sox2

• UniProt:

  P48431

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide corresponding to the N-terminus of the human Sox2.

• Target:

  SOX; ANOP; MCOPS; SRY-box; ANOP3; MCOPS3; SOX2; SRY-box 2; cb236; Delta EF2a; lcc; MGC148683; MGC2413; RGD1565646; Sex determining region Y box 2; SOX 2; SRY (sex determining region Y) box 2; SRY box containing gene 2; SRY related HMG box 2; SRY related HMG box gene 2; Transcription factor SOX 2; Transcription factor SOX-2; ysb; ANOP3; MCOPS3; Sox2; SRY-box 2

• Clonality:

  Monoclonal

• Clone:

  3G4

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Neuroscience; Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  34 kDa

• Observed Molecular Weight:

  37 kDa

• Isotype:

  IgG