Products for Research Use Only
RegisterLogin

Panaxadiol

CAT: 0804-HY-N0596-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0596-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Panaxadiol (20 (R) -Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 then lead to downregulation of programmed cell death-ligand 1 (PD-L1) expression. Panaxadiol shows anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities[1][2].
CAS Number
19666-76-3
Product Name Alternative
20 (R) -Panaxadiol
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HIF/HIF Prolyl-Hydroxylase; PD-1/PD-L1; STAT
Type
Natural Products
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Panaxadiol.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 20 mg/mL (ultrasonic)
Smiles
C[C@@]1(CC[C@@H]2O)[C@](C[C@H]3O)([H])[C@](CC[C@@]1([H])C2(C)C)(C)[C@@]4(C)[C@@]3([H])[C@]([C@](CCC5)(C)OC5(C)C)([H])CC4
Molecular Formula
C30H52O3
Molecular Weight
460.73
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang Z, et al. Panaxadiol inhibits programmed cell death-ligand 1 expression and tumour proliferation via hypoxia-inducible factor (HIF) -1α and STAT3 in human colon cancer cells. Pharmacol Res. 2020;155:104727.|[2]Myong Hak Ri, et al. Development of natural products for anti-PD-1/PD-L1 immunotherapy against cancer. J Ethnopharmacol. 2021 Dec 5;281:114370.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N3114-01Panaxydiol
HY-N0597-01Panaxatriol
HY-N0597RPanaxatriol (Standard)

Alternative Products

CatalogName
300753Panaxadiol
A14525-50Panaxadiol 50mg
A14525-100Panaxadiol 100mg
A14525-25Panaxadiol 25mg

Popular Products