DL-Sulforaphane N-acetyl-L-cysteine

• Product Name Alternative:

  SFN-NAC

• UNSPSC Description:

  DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is an orally active HDAC inhibitor and metabolite of sulforaphane (HY-13755) with longer half-life and better blood-brain barrier permeability. DL-Sulforaphane N-acetyl-L-cysteine activates autophagy-mediated downregulation of α-tubulin expression through the ERK pathway and can be used in cancer research[1][2].

• Target Antigen:

  Apoptosis; Drug Metabolite; HDAC

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dl-sulforaphane-n-acetyl-l-cysteine.html

• Purity:

  99.90

• Solubility:

  DMSO : 10 mg/mL (ultrasonic;warming)

• Smiles:

  CS(CCCCNC(SC[C@@H](C(O)=O)NC(C)=O)=S)=O

• Molecular Weight:

  340.48

• References & Citations:

  [1]Liu HJ, et al. Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells. Cell Physiol Biochem. 2018;51(2):528-542.|[2]Dashwood R H, et al. Dietary histone deacetylase inhibitors: from cells to mice to man[C]//Seminars in cancer biology. Academic Press, 2007, 17(5): 363-369.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  334829-66-2