β-Amyrenonol

CAT: 0804-HY-N2920-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N2920-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids[1][2].
CAS Number
[38242-02-3]
Product Name Alternative
11-Oxo-β-amyrin
UNSPSC
12352211
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/β-amyrenonol.html
Purity
99.31
Solubility
10 mM in DMSO
Smiles
C[C@@]1([C@@]2([H])[C@@]3([C@@](C(C)([C@@H](O)CC3)C)([H])CC1)C)[C@]4(C([C@@]5([H])[C@](C)(CCC(C)(C)C5)CC4)=CC2=O)C
Molecular Formula
C30H48O2
Molecular Weight
440.70
References & Citations
[1]James Reed, et al. A Translational Synthetic Biology Platform for Rapid Access to Gram-Scale Quantities of Novel Drug-Like Molecules. Metab Eng. 2017 Jul;42:185-193.|[2]Ming Zhu, et al. Boosting 11-oxo-β-amyrin and Glycyrrhetinic Acid Synthesis in Saccharomyces Cerevisiae via Pairing Novel Oxidation and Reduction System From Legume Plants. Metab Eng. 2018 Jan;45:43-50.|[3]Hikaru Seki, et al. Licorice Beta-Amyrin 11-oxidase, a Cytochrome P450 With a Key Role in the Biosynthesis of the Triterpene Sweetener Glycyrrhizin. Proc Natl Acad Sci U S A. 2008 Sep 16;105 (37) :14204-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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