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Doxylamine

CAT: 0804-HY-A0069ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-A0069ASize:1 Each
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Description
Doxylamine, a first generation antihistamine, is a histamine (H1) receptor antagonist. Doxylamine is also a local analgesic agent and effective hypnotic agent[1][2][3].
CAS Number
[469-21-6]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/doxylamine.html
Solubility
10 mM in DMSO
Smiles
CC(C1=NC=CC=C1)(C2=CC=CC=C2)OCCN(C)C
Molecular Formula
C17H22N2O
Molecular Weight
270.37
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[2]Hung CH, et al. Subcutaneous infiltration of doxylamine on cutaneous analgesia in rats. Pharmacol Rep. 2018;70 (3) :565-569.|[3]Jackson CD, Blackwell BN. Subchronic studies of doxylamine in B6C3F1 mice. Fundam Appl Toxicol. 1988;10 (2) :254-261.|[1]Sjöqvist F, Lasagna L. The hypnotic efficacy of doxylamine. Clin Pharmacol Ther. 1967;8 (1) :48-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor

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