Products for Research Use Only
RegisterLogin

Corr4A

CAT: 0804-HY-117187-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-117187-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Corr4A is a chemical corrector, which can be used for cystic fibrosis. Corr4A interacts directly with the cystic fibrosis transmembrane conductance regulator (CFTR) or affects indirectly its folding process. Corr4A increases the expression of CFTR ΔF508 on the cell surface, thereby improving its transport to the plasma membrane and increasing the stability of the rescued mutant protein[1].
CAS Number
421580-53-2
UNSPSC
12352005
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/corr4a.html
Purity
98.36
Smiles
O=C(NC1=NC(C)=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)S1)C4=CC=CC=C4
Molecular Formula
C21H17ClN4O2S2
Molecular Weight
456.97
References & Citations
[1]Grove DE, et al., Mechanisms for rescue of correctable folding defects in CFTRDelta F508. Mol Biol Cell. 2009 Sep;20 (18) :4059-69.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-RS03051CORO2A Human Pre-designed siRNA Set A
HY-P88175-01CORO1A (Coronin 1a) Antibody (YA7859, Mouse)
HY-RS03048CORO1A Human Pre-designed siRNA Set A
HY-RS28357Coro1a Rat Pre-designed siRNA Set A
HY-RS21841Coro1a Mouse Pre-designed siRNA Set A

Alternative Products

CatalogName
BA6629-1Corr4A

Popular Products