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Epiblastin A

CAT: 0804-HY-114858-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114858-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC50s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1[1].
CAS Number
16470-02-3
Product Name Alternative
BAY1163877
UNSPSC
12352005
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/epiblastin-a.html
Purity
99.44
Solubility
DMSO : 4.55 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=NC(N)=C2N=C(C(N)=NC2=N1)C3=CC=CC(Cl)=C3
Molecular Formula
C12H10ClN7
Molecular Weight
287.71
References & Citations
[1]Andrei Ursu, et al. Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol. 2016 Apr 21;23 (4) :494-507.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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MBS3613403-01Epiblastin A
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A22121-50Epiblastin A 50mg
A22121-5Epiblastin A 5mg
A22121-100Epiblastin A 100mg
A22121-200Epiblastin A 200mg
A22121-25Epiblastin A 25mg

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