Levofloxacin N-oxide

• UNSPSC Description:

  Levofloxacin N-oxide is a minor metabolite of Levofloxacin (HY-B0330). Levofloxacin N-oxide does not exhibit significantly genotoxic risks. Levofloxacin is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria[1][2].

• Target Antigen:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/levofloxacin-n-oxide.html

• Smiles:

  O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CC[N+](C)([O-])CC4)C(F)=CC1=C23)O

• Molecular Weight:

  377.37

• References & Citations:

  [1]Zhu Q, et al. In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin. Toxicol Mech Methods. 2012 Apr;22(3):225-30.|[2]Nightingale CH, et al. Pharmacodynamics and pharmacokinetics of levofloxacin. Chemotherapy. 2000;46 Suppl 1:6-14.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  117678-38-3