Octocrylene (Standard)

• Description:

  Octocrylene (Standard) is the analytical standard of Octocrylene. This product is intended for research and analytical applications. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H400, H410

• Target:

  Biochemical Assay Reagents; Cytochrome P450; Estrogen Receptor/ERR; PPAR; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/octocrylene-standard.html

• Purity:

  98.08

• Smiles:

  O=C(OCC(CC)CCCC)/C(C#N)=C(C1=CC=CC=C1)\C2=CC=CC=C2

• Molecular Formula:

  C24H27NO2

• Molecular Weight:

  361.48

• Precautions:

  H400, H410

• References & Citations:

  [1]E Berardesca, et al. Review of the safety of octocrylene used as an ultraviolet filter in cosmetics. J Eur Acad Dermatol Venereol. 2019 Nov;33 Suppl 7:25-33.|[2]Vatan Ö, et al. Evaluation of cytotoxic and genotoxic potential of avobenzone and octocrylene on human skin fibroblast cells[J]. All Life, 2023, 16 (1) : 2270171.|[3]Meng Q, et al. Toxic effects of octocrylene on zebrafish larvae and liver cell line (ZFL) [J]. Aquatic Toxicology, 2021, 236: 105843.|[4]Ko H, et al. Sunscreen filter octocrylene is a potential obesogen by acting as a PPARγ partial agonist[J]. Toxicology letters, 2022, 355: 141-149.|[5]de Groot A C, et al. Contact and photocontact allergy to octocrylene: a review[J]. Contact dermatitis, 2014, 70 (4) : 193-204.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, sealed and dry storage, away from light and moisture

• Scientific Category:

  Reference Standards

• CAS Number:

  6197-30-4