Orientin

• Description :

  Orientin is a neuroprotective agentinhibits which has anti-inflammation, anti-oxidative, anti-tumor, and cardio protection properties. Orientin inhibits the levels of IL-6, IL-1β and TNF-α. Orientin increases IL-10 level. Orientin exhibits neuroprotective effect by inhibits TLR4 and NF-kappa B signaling pathway. Orientin can used in study neuropathic pain[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H312, H332

• Target :

  Interleukin Related; TNF Receptor

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/orientin.html

• Purity :

  99.73

• Solubility :

  DMSO : 31.25 mg/mL (ultrasonic)

• Smiles :

  O[C@@H]1[C@@H](O)[C@H](C2=C(O)C=C(O)C3=C2OC(C4=CC=C(O)C(O)=C4)=CC3=O)O[C@H](CO)[C@H]1O

• Molecular Formula :

  C21H20O11

• Molecular Weight :

  448.38

• Precautions :

  H302, H312, H332

• References & Citations :

  [1]Dhakal H, et al. Inhibitory effects of orientin in mast cell-mediated allergic inflammation. Pharmacol Rep. 2020 Jan 24.|[2]Guo D, et al. Orientin and neuropathic pain in rats with spinal nerve ligation. 61Int Immunopharmacol. 2018 May;58:72-79.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [28608-75-5]