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ST7612AA1

CAT: 0804-HY-12926-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12926-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ST7612AA1 is a histone deacetylase (HDAC) inhibitor that controls chromatin condensation and DNA transcription by removing acetyl groups from histones. ST7612AA1 is also a potent HIV reactivation inducer, and its reactivation activity is exerted without activating or proliferating CD4+T cells, and can be used in the study of HIV reactivation strategies and elimination of viral reservoirs[1].
CAS Number
1428535-92-5
UNSPSC
12352005
Target
DNA/RNA Synthesis; HDAC; HIV
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Epigenetics
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/st7612aa1.html
Smiles
CC(SCCCCC[C@H](NC([C@@H](CC1)NC1=O)=O)C(NC2=CC=CC=C2)=O)=O
Molecular Formula
C20H27N3O4S
Molecular Weight
405.51
References & Citations
[1]Badia, et al. The thioacetate-ω (γ-lactam carboxamide) HDAC inhibitor ST7612AA1 as HIV-1 latency reactivation agent. Antiviral research 123 (2015) : 62-69.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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