Products for Research Use Only
RegisterLogin

Fmoc-MMAF-OMe

CAT: 0804-HY-79255-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-79255-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Fmoc-MMAF-OMe is an anticancer agent and tubulin polymerization inhibitor with an Fmoc protecting group. The active ingredient of Fmoc-MMAF-OMe, MMAF , is the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs).
CAS Number
863971-38-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ADC Payload; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-mmaf-ome.html
Concentration
10mM
Purity
98.58
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C(OC)=O)CC2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)C)=O)=O)C
Molecular Formula
C55H77N5O10
Molecular Weight
968.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee JW, et al. EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma. Clin Cancer Res. 2010 May 1;16 (9) :2562-70. [Content Brief]
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-79256-01MMAF-OMe
HY-155744Acetylene-PEG3-MMAF-OMe
HY-W041988-01Fmoc-Glu-OMe
HY-W072147-01Fmoc-Ser-OMe
HY-W041982-01Fmoc-Asp-OMe
HY-W019028-01Fmoc-Lys-OMe.HCl
HY-W008256-01Fmoc-Glu (OMe) -OH
HY-15579-01MMAF
HY-136287-01DBM-MMAF
HY-139326-01NHS-MMAF

Alternative Products

CatalogName
BA2363-10Fmoc-MMAF-OMe
BA2334-100MMAF-OMe
A20540-10MMAF-OMe 10mg
A20540-5MMAF-OMe 5mg
A20540-2MMAF-OMe 2mg
A20540-100MMAF-OMe 100mg
A20540-50MMAF-OMe 50mg
A20540-25MMAF-OMe 25mg
GTR19237586-01Acetylene-PEG3-MMAF-OMe
BA1403-100000Fmoc-Glu-OMe

Popular Products