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WBC100

CAT: 0804-HY-145898-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145898-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc molecule glue degrader. WBC100 is a c-Myc degrader and targets ubiquitin E3 ligase CHIP mediated 26S proteasome pathway. WBC100 is used for c-Myc overexpressing tumors research[1].
CAS Number
2095780-08-6
Product Name Alternative
14-D-Valine-TPL
UNSPSC
12352005
Target
C-Myc; Molecular Glues
Type
Reference compound
Related Pathways
Apoptosis; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wbc100.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]([C@@]1([H])C2)(CCC3=C1COC3=O)[C@]4([C@@]([C@@](O5)([H])[C@@]65C(C)C)([H])O4)[C@@]7([C@@]2([H])O7)[C@@H]6OC([C@H](N)C(C)C)=O
Molecular Formula
C25H33NO7
Molecular Weight
459.53
References & Citations
[1]Ying Xu, et al. A Selective Small-Molecule c-Myc Degrader Potently Regresses Lethal c-Myc Overexpressing Tumors. Adv Sci (Weinh) . 2022 Mar;9 (8) :e2104344.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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CatalogName
BA3367-5.1WBC100

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