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Vutiglabridin

CAT: 0804-HY-145605-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145605-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vutiglabridin (HSG4112), a racemic compound, is a potent anti-obesity agent[1]. Vutiglabridin, an optimized structural analog of Glabridin, markedly supersedes Glabridin in weight reduction efficacy and chemical stability[1].
CAS Number
1800188-47-9
Product Name Alternative
HSG4112
UNSPSC
12352005
Target
Bacterial; PPAR; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/vutiglabridin.html
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC(OCC)=CC=C1C2COC3=C4CCC(C)(C)OC4=CC=C3C2
Molecular Formula
C22H26O4
Molecular Weight
354.44
References & Citations
[1]In Yong Bae, et al. Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent. Pharmaceutics. 2020 Feb 3;12 (2) :127.|[2]Leo Sungwong Choi, et al. Discovery and preclinical efficacy of HSG4112, a synthetic structural analog of glabridin, for the treatment of obesity. Int J Obes (Lond) . 2021 Jan;45 (1) :130-142.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
BUP08482-01Vutiglabridin

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