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Pratol

CAT: 0804-HY-N8719-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N8719-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pratol is a potent inhibitor of NF-κB. Pratol significantly reduces NO and prostaglandin PGE2 production without any cytotoxic in LPS-stimulated RAW 264.7 cells. Pratol reduces proinflammatory cytokines. Pratol can be used in study inflammatory diseases and cancer[1].
CAS Number
487-24-1
Product Name Alternative
7-Hydroxy-4'-methoxyflavone
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pratol.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(O)=CC=C13
Molecular Formula
C16H12O4
Molecular Weight
268.26
Precautions
H302, H312, H332
References & Citations
[1]Chung, Y. C. , et al. Anti-inflammatory Effect of Pratol in LPS-stimulated RAW 264.7 Cells via NF-κB Signaling Pathways. Natural Product Communications, 13 (5), 1934578X1801300.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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