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HAMNO

CAT: 0804-HY-111285-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-111285-02Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HAMNO is a novel protein interaction inhibitor of replication protein A (RPA) .
CAS Number
138736-73-9
Product Name Alternative
NSC111847
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/HAMNO.html
Purity
99.89
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C=CC1=C/2C=CC=C1)C2=C/NC3=CC=CC=C3O
Molecular Formula
C17H13NO2
Molecular Weight
263.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Glanzer JG, et al. RPA inhibition increases replication stress and suppresses tumor growth. Cancer Res. 2014 Sep 15;74 (18) :5165-72.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

1-(((2-Hydroxyphenyl)imino)methyl)-2-naphthalenol
CAS Number138736-73-9
PubChem CID85895
IUPAC Name1-[(2-hydroxyphenyl)iminomethyl]naphthalen-2-ol
Molecular FormulaC17H13NO2
Molecular Weight263.29
XLogP3.8
Topological Polar Surface Area52.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity344
SMILES
C1=CC=C2C(=C1)C=CC(=C2C=NC3=CC=CC=C3O)O
InChI
InChI=1S/C17H13NO2/c19-16-10-9-12-5-1-2-6-13(12)14(16)11-18-15-7-3-4-8-17(15)20/h1-11,19-20H
InChIKey
FMIVOPRNBGRDKP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(((2-Hydroxyphenyl)imino)methyl)-2-naphthalenol
CAS: 138736-73-9
CID: 85895
Formula: C17H13NO2
MW: 263.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight263.29
XLogP33.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass263.094628657
Monoisotopic Mass263.094628657
Topological Polar Surface Area52.8 Ų
Heavy Atom Count20
Formal Charge0
Complexity344
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
C07029-5mgHAMNO
A17054-25HAMNO 25mg
A17054-5HAMNO 5mg
A17054-50HAMNO 50mg
A17054-100HAMNO 100mg
A17054-10HAMNO 10mg
A17054-10mM-DHAMNO 10mM * 1mL in DMSO

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