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RO3244794

CAT: 0804-HY-164580-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-164580-01Size:1 mg
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Description
RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pKi of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential[1].
CAS Number
361457-01-4
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ro3244794.html
Purity
99.64
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
FC(C=C1)=CC=C1C[C@H](C(O)=O)NC(OCC2=CC3=CC(C4=CC=C(C=C4)F)=CC=C3O2)=O
Molecular Formula
C25H19F2NO5
Molecular Weight
451.42
References & Citations
[1]Bley KR, et, al. RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists. Br J Pharmacol. 2006 Feb;147 (3) :335-45.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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MBS5811909RO3244794

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