Products for Research Use Only
RegisterLogin

Apitegromab

CAT: 0804-HY-P99441-01Size: 1 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P99441-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy[1][2].
CAS Number
2278276-46-1
Product Name Alternative
SRK-015
UNSPSC
12352203
Target
TGF-beta/Smad
Type
Inhibitory Antibodies
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/apitegromab.html
Purity
99.51
Solubility
10 mM in DMSO
Smiles
[Apitegromab]
Molecular Weight
(145.06 kDa)
References & Citations
[1]Doreen Barrett, et al. A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015) : A Potential Treatment for Spinal Muscular Atrophy. Adv Ther. 2021 Jun;38 (6) :3203-3222. |[2]Welsh BT, et al. Preclinical Safety Assessment and Toxicokinetics of Apitegromab, an Antibody Targeting Proforms of Myostatin for the Treatment of Muscle-Atrophying Disease. Int J Toxicol. 2021 Jul-Aug;40 (4) :322-336.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3

Alternative Products

CatalogName
T77445-01Apitegromab
GTR18333594-01Apitegromab Antibody
HT343056-01Research Grade Apitegromab
E55B0897Apitegromab (Reference antibody)
ICH5228-5mgApitegromab Biosimilar - Research Grade
A138306Apitegromab Biosimilar (Monoclonal, IgG4)
C00281-1mg*5Apitegromab (Anti-GDF8 / Myostatin)
GTR18697203-01Apitegromab Human Monoclonal Antibody
F1693-.1Anti-GDF8/Myostatin Antibody (Apitegromab)
12-90059-100Anti-GDF8 (apitegromab biosimilar) mAb

Popular Products