Nicardipine (hydrochloride) (Standard)

Nicardipine (hydrochloride) (Standard)

• CAS Number: 54527-84-3
• UNSPSC Description: Nicardipine (hydrochloride) (Standard) is the analytical standard of Nicardipine (hydrochloride). This product is intended for research and analytical applications. Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure[1].
• Target Antigen: Autophagy; Calcium Channel
• Type: Reference Standards
• Related Pathways: Autophagy;Membrane Transporter/Ion Channel;Neuronal Signaling
• Field of Research: Neurological Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/nicardipine-hydrochloride-standard.html
• Purity: 99.65
• Smiles: O=C(C1=C(C)NC(C)=C(C(OCCN(C)CC2=CC=CC=C2)=O)C1C3=CC=CC([N+]([O-])=O)=C3)OC.[H]Cl
• Molecular Weight: 515.99
• References & Citations: [1]Charnet P, et al. Electrophysiological analysis of the action of nifedipine and nicardipine on myocardial fibers. Fundam Clin Pharmacol. 1987;1(6):413-31.|[2]R Stamatiou, et al. The dihydropyridine calcium antagonist nicardipine reduces aortic smooth muscle cell viability, proliferation and migration. Cardiovascular Research, 2018 Apr,114(1):S43.|[3]Sherrin H. Baky. Nic ardipine Hydrochloride.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: Launched