S49076

S49076

• CAS Number: 1265965-22-7
• UNSPSC Description: S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.
• Target Antigen: c-Met/HGFR; FGFR
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/S49076.html
• Purity: 99.44
• Solubility: DMSO : ≥ 31 mg/mL
• Smiles: O=C(N1CC2=CC3=C(NC(/C3=C\C4=CC(CN5CCOCC5)=CN4)=O)C=C2)SCC1=O
• Molecular Weight: 438.50
• References & Citations: [1]Burbridge MF, et al. S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. Mol Cancer Ther. 2013 Sep;12(9):1749-62.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported