Amdoxovir

CAT: 0804-HY-106155Size: 1 EachDry Ice: NoHazardous: No

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Description

Amdoxovir (DAPD) is an orally active nucleoside reverse transcriptase inhibitor. Amdoxovir is active against wild-type and NRTl-resistant viruses. Amdoxovir is the prodrug of dioxolane guanosine. Amdoxovir can be used for research of HIV/AIDS[1].

CAS Number

145514-04-1

Product Name Alternative

DAPD

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

HIV; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/amdoxovir.html

Smiles

NC1=C2C(N([C@@H]3O[C@@H](OC3)CO)C=N2)=NC(N)=N1

Molecular Formula

C9H12N6O3

Molecular Weight

252.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Gripshover BM, et al. Amdoxovir versus placebo with enfuvirtide plus optimized background therapy for HIV-1-infected subjects failing current therapy (AACTG A5118) . Antivir Ther. 2006;11 (5) :619-23.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

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