GLα/Galactosidase Alpha Polyclonal Antibody

• Background:

  Alpha -Galactosidase A is a homodimeric glycoprotein that can release terminal alpha -galactosyl moieties from glycolipids and glycoproteins and catalyze the hydrolysis of melibiose into galactose and glucose . It is a lysosomal enzyme and is responsible for degradation of glycolipid globotriaosylceramide (Gb3) (Gal alpha 1‑4Gal beta 1‑4Glc beta ‑ceramide) . Mutations in this gene cause Fabry disease, an X-linked hereditary lysosomal storage disease with the accumulation of Gb3 in the walls of small blood vessels, nerves, dorsal root ganglia, renal glomerular and tubular epithelial cells, and cardiomyocytes.

• Abbreviation:

  GLα

• UniProt:

  P06280

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human GLα/Galactosidase Alpha protein expressed by Mammalian

• Target:

  GLA; GALA; Alpha-D-Galactoside; Galactohydrolase; galactosidase alpha; GLAL; Melibiase; Agalsidase; Alpha-galactosidase A; Alpha-D-galactosidase A; Alpha-D-galactoside galactohydrolase; Galactosylgalactosylglucosylceramidase GLA

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cardiovascular

• Purification:

  Antigen Affinity Purification

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000; IHC 1:1000-1:2000

• Buffer:

  PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  49 kDa

• Observed Molecular Weight:

  49 kDa

• Isotype:

  IgG