1H-pyrazole

CAT: 0804-HY-76228-01Size: 10 gDry Ice: NoHazardous: No
CAT#:0804-HY-76228-01Size:10 g
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Description
1H-pyrazole is a nitrogen-containing heterocyclic compound composed of a five-membered ring and two nitrogen atoms. 1H-pyrazole is an intermediate in organic synthesis. 1H-pyrazole coordinates with metal ions. 1H-pyrazole derivatives have antibacterial, anti-inflammatory, anti-malarial, and anti-leishmanial activities[1][2][3][4].
CAS Number
[288-13-1]
Product Name Alternative
Pyrazole
UNSPSC
12352005
Hazard Statement
H302, H311, H315, H318, H373, H412
Target
Biochemical Assay Reagents; Drug Intermediate
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/1h-pyrazole.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N1=CC=CN1
Molecular Formula
C3H4N2
Molecular Weight
68.08
Precautions
H302, H311, H315, H318, H373, H412
References & Citations
[1]Bekhit AA, et al. Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents. Eur J Med Chem. 2008 Mar;43 (3) :456-63.|[2]Vyas KM, et al. Synthesis, spectroscopic characterization and DNA nuclease activity of Cu (II) complexes derived from pyrazolone based NSO-donor Schiff base ligands. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Dec 15;84 (1) :256-68.|[3]Jhuang J Y, et al. Adsorption and reaction pathways of 1H-pyrazole on Cu (100) and O/Cu (100) . The Journal of Physical Chemistry C, 2018, 122 (11) : 6195-6208.|[4]Bekhit AA, et al. Evaluation of some 1H-pyrazole derivatives as a dual acting antimalarial and anti-leishmanial agents. Pak J Pharm Sci. 2014 Nov;27 (6) :1767-73. PMID: 25362601.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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