Amphimedine

• Description :

  Amphimedine is a polycyclic alkaloid isolated from the marine sponge Amphimedon sp. and belongs to the pyridoindole alkaloid class. Amphimedine has cytotoxic activity and has been studied as an anticancer metabolite along with neoamphimedine. Studies have shown that deoxyamphimedine damages DNA by generating reactive oxygen species, a mechanism different from that of amphimedine.

• CAS Number :

  [86047-14-5]

• UNSPSC :

  12352005

• Target :

  Reactive Oxygen Species (ROS)

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/amphimedine.html

• Smiles :

  O=C(C1=NC=CC2=C3C=CC=CC3=NC(C4=CC5=O)=C12)C4=CN5C

• Molecular Formula :

  C19H11N3O2

• Molecular Weight :

  313.31

• References & Citations :

  [1]Deoxyamphimedine, a New Pyridoacridine Alkaloid from Two Tropical Xestospongia Sponges

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported