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Panitumumab

CAT: 0804-HY-P99041-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99041-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer[1][2][4].
CAS Number
339177-26-3
Product Name Alternative
ABX-EGF
UNSPSC
12352203
Target
EGFR
Type
Inhibitory Antibodies
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/panitumumab.html
Purity
99.77
Solubility
H2O
Smiles
[Panitumumab]
Molecular Weight
(144.32 kDa)
References & Citations
[1]Yu Jo Chua, et al. Panitumumab. Drugs Today (Barc) . 2006 Nov;42 (11) :711-9.|[2]Stefan Stremitzer, et al. Panitumumab safety for treating colorectal cancer. Expert Opin Drug Saf. 2014 Jun;13 (6) :843-51.|[3]Daniel J. Freeman, et al. Activity of panitumumab alone or with chemotherapy in non-small cell lung carcinoma cell lines expressing mutant epidermal growth factor receptor. Mol Cancer Ther (2009) 8 (6) : 1536–1546.|[4]Efstathia Giannopoulou, et al. Autophagy: novel action of panitumumab in colon cancer. Anticancer Res. 2009 Dec;29 (12) :5077-82.|[5]Giannopoulou E, et al. Autophagy: novel action of panitumumab in colon cancer. Anticancer Res. 2009 Dec;29 (12) :5077-82. PMID: 20044619.. . .
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched

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