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Graphislactone A

CAT: 0804-HY-122985-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122985-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Graphislactone A is an antioxidant, which is found in Cephalosporium IFB-E001 and M. olivacea. Graphislactone A inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM. Graphislactone A is promising for research of oxidative damage-initiated diseases[1][2].
CAS Number
52179-44-9
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/graphislactone-a.html
Smiles
O=C1OC2=C(C(OC)=CC(C)=C2C3=CC(OC)=CC(O)=C13)O
Molecular Formula
C16H14O6
Molecular Weight
302.28
References & Citations
[1]Song YC, et al. Characterization of graphislactone A as the antioxidant and free radical-scavenging substance from the culture of Cephalosporium sp. IFB-E001, an endophytic fungus in Trachelospermum jasminoides. Biol Pharm Bull. 2005 Mar;28 (3) :506-9. |[2]Hormazabal E, et al. Metabolites from Microsphaeropsis olivacea, an endophytic fungus of Pilgerodendron uviferum. Z Naturforsch C J Biosci. 2005 Jan-Feb;60 (1-2) :11-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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