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RSC133

CAT: 0804-HY-12310-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12310-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RSC133 exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. RSC133 effectively facilitates reprogramming of human somatic cells to pluripotent stem cells and supports the maintenance of an undifferentiated state of human pluripotent stem cells[1].
CAS Number
1418131-46-0
UNSPSC
12352005
Hazard Statement
H302, H411
Target
DNA Methyltransferase; HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rsc133.html
Purity
98.45
Solubility
DMSO : 20 mg/mL (ultrasonic; warming)
Smiles
NC(C1=CC=CC(NC(/C=C/C2=CNC3=CC=CC=C23)=O)=C1)=O
Molecular Formula
C18H15N3O2
Molecular Weight
305.33
Precautions
H302, H411
References & Citations
[1]Lee J, et al. A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells. Angew Chem Int Ed Engl. 2012 Dec 7;51 (50) :12509-13.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported