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Piperine (Standard)

CAT: 0804-HY-N0144R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0144R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Piperine (Standard) is the analytical standard of Piperine. This product is intended for research and analytical applications. Piperine is an alkaloid, can be isolated from pepper. Piperine can inhibit the activity of P-glycoprotein and CYP3A4. Piperine inhibits HeLa cells with an IC50 of 61.94±0.054 μg/mL[1][2][3].
CAS Number
94-62-2
Product Name Alternative
Bioperine (Standard) ; 1-Piperoylpiperidine (Standard)
UNSPSC
12352005
Hazard Statement
H302, H401, H411
Target
Autophagy; Endogenous Metabolite; P-glycoprotein; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/piperine-standard.html
Purity
98.55
Smiles
O=C(N1CCCCC1)/C=C/C=C/C2=CC=C(OCO3)C3=C2
Molecular Formula
C17H19NO3
Molecular Weight
285.34
Precautions
H302, H401, H411
References & Citations
[1]Paarakh PM, et al. In vitro cytotoxic and in silico activity of piperine isolated from Piper nigrum fruits Linn. In Silico Pharmacol. 2015 Dec;3 (1) :9. Epub 2015 Oct 29.|[2]Meghwal M, et al. Piper nigrum and piperine: an update. Phytother Res. 2013 Aug;27 (8) :1121-30.|[3]Li C, et al. Non-linear pharmacokinetics of piperine and its herb-drug interactions with docetaxel in Sprague-Dawley rats. J Pharm Biomed Anal. 2016 Sep 5;128:286-93.|[4]Zhai WJ, et al. Piperine Plays an Anti-Inflammatory Role in Staphylococcus aureus Endometritis by Inhibiting Activation of NF-κB and MAPK Pathways in Mice. Evid Based Complement Alternat Med. 2016;2016:8597208.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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