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Cleaved-NOTCH2 (A1734) Antibody

CAT: 0864-A33588-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0864-A33588-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
AGS2, hN2, Motch B, N2, N2ECD, N2ICD, neurogenic locus notch homolog protein 2, NOTC2_HUMAN, Notch 2, Notch 2 intracellular domain, Notch Drosophila homolog 2, Notch homolog 2, Notch homolog 2 Drosophila, Notch2
UniProt
Q04721
Host
Rabbit
Antigen Species
Human
Reactivity
Human, Mouse, Rat
Target Antigen
Synthesized peptide derived from the Internal region of Human Notch 2.
Target
NOTCH2
Clonality
Polyclonal
Conjugation
Non-conjugated
Applications
WB, ELISA, WB:1:500-1:2000, ELISA:1:10000
Field of Research
Neuroscience
Purification Method
Antigen affinity purified
Form
Liquid
Buffer
PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide, pH 7.4.
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Fragment
IgG

UniProtKB · Q04721

Neurogenic locus notch homolog protein 2

NOTC2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q04721
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOTCH2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Notch 2, hN2
EC number
—
Processing
Precursor
Secondary accessions
Q5T3X7, Q99734, Q9H240
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Cellular component

Cell membraneCytoplasmMembraneNucleus

Biological process

DifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Disease

Disease variantOsteoporosis

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

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