Tetrazine-PEG7-amine (hydrochloride)

Tetrazine-PEG7-amine (hydrochloride)

• UNSPSC Description: Tetrazine-PEG7-amine hydrochloride is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG7-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
• Target Antigen: ADC Linker
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/tetrazine-peg7-amine-hydrochloride.html
• Solubility: DMSO : 200 mg/mL (ultrasonic)
• Smiles: O=C(CCOCCOCCOCCOCCOCCOCCOCCN)NCC(C=C1)=CC=C1C2=NN=CN=N2.Cl
• Molecular Weight: 603.11
• References & Citations: [1]Beck A, et, al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported