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Peresolimab

CAT: 0804-HY-P9993-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P9993-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Peresolimab is a humanized IgG1-κ antibody targeting to PD-1. Peresolimab potentially stimulates physiological immune inhibitory pathways to restore immune homeostasis. Peresolimab can be used in research of rheumatoid arthritis[1][2].
CAS Number
2411580-63-5
Product Name Alternative
LY-3462817
UNSPSC
12352203
Target
PD-1/PD-L1
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/peresolimab.html
Purity
99.62
Solubility
10 mM in DMSO|H2O
Smiles
[Peresolimab]
Molecular Weight
(145.16 kDa)
References & Citations
[1]Tuttle J, et al. Phase 2 Trial of Peresolimab for Adults with Rheumatoid Arthritis. Reply. N Engl J Med. 2023 Jul 27;389 (4) :378-379.|[2]Leane CM, et al., PD-1 regulation of pathogenic IL-17-secreting γδ T cells in experimental autoimmune encephalomyelitis. Eur J Immunol. 2024 Oct;54 (10) :e2451212.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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