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Maribavir

CAT: 0804-HY-16305-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-16305-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus (EBV) .
CAS Number
176161-24-3
Product Name Alternative
1263W94; BW1263W94; GW257406X
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CMV; EBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Maribavir.html
Purity
99.96
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
ClC1=C(Cl)C=C2C(N=C(NC(C)C)N2[C@@H]3[C@@H](O)[C@@H](O)[C@H](CO)O3)=C1
Molecular Formula
C15H19Cl2N3O4
Molecular Weight
376.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Shannon-Lowe CD, et al. The effects of Maribavir on the autophosphorylation of ganciclovir resistant mutants of the cytomegalovirus UL97 protein. Herpesviridae. 2010 Dec 7;1 (1) :4.|[2]Biron KK, et al. Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action. Antimicrob Agents Chemother. 2002 Aug;46 (8) :2365-72.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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