CXCL16, Rat (HEK293, Fc)

CXCL16, Rat (HEK293, Fc)

• UNSPSC Description: CXCL16, also known as SR-PSOX (scavenger receptor that binds phosphatidylserine and oxidized lipoprotein), is one member of the ELR-negative CXC chemokine subfamily. CXCL16 is a multifunctional protein involved in various inflammatory diseases, atherosclerosis, and cancer. CXCL16 can be observed in many cell types[1][2]. CXCL16 Protein, Rat (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/cxcl16-protein-rat-hek293-fc.html
• Molecular Weight: Approximately 67 kDa
• References & Citations: [1]Tohyama M, et al. CXCL16 is a novel mediator of the innate immunity of epidermal keratinocytes. Int Immunol. 2007 Sep;19(9):1095-102.|[2]Jianhui Sun, et al. A Functional Variant of CXCL16 Is Associated With Predisposition to Sepsis and MODS in Trauma Patients: Genetic Association Studies. Front Genet. 2021 Sep 3;12:720313.|[3]Allaoui R, et al. Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers. Nat Commun. 2016 Oct 11;7:13050.|[4]Yojiro Sakuma, et al. Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice. Sci Rep. 2018 Jun 11;8(1):8829.
• Shipping Conditions: Room temperature