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CGP35348

CAT: 0804-HY-103530-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103530-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only[1]. CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage[2].
CAS Number
123690-79-9
UNSPSC
12352211
Hazard Statement
H302, H318, H410
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cgp35348.html
Purity
98.0
Solubility
H2O : 83.33 mg/mL (ultrasonic)
Smiles
O=P(C(OCC)OCC)(CCCN)O
Molecular Formula
C8H20NO4P
Molecular Weight
225.22
Precautions
H302, H318, H410
References & Citations
[1]H R Olpe, et al. CGP 35348: a centrally active blocker of GABAB receptors. CGP 35348: a centrally active blocker of GABAB receptors|[2]Q Gillani, et al. CGP 35348, GABA B receptor antagonist, has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage. Biomed Res Int. 2014;2014:295215. |[3]A Puigcerver, et al. Effects of the GABAB antagonist CGP 35348 on sleep-wake states, behaviour, and spike-wave discharges in old rats. Brain Res Bull. 1996;40 (3) :157-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
217271CGP 35348 (GABAB Receptor Antagonist, CGP 35348, CGP35348, CGP-35348)

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