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PHM16

CAT: 0804-HY-117595Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117595Size:1 Each
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Description
PHM16 is an ATP competitive inhibitor of FAK and FGFR2 (IC50: 0.4 μM and 0.37 μM, respectively), with direct potent anti-angiogenic activity[1].
CAS Number
1448791-29-4
UNSPSC
12352005
Target
Apoptosis; FAK; FGFR
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/phm16.html
Smiles
O=C(C1=C(NC2=NC(NC3=CC(OC)=C(C(OC)=C3)OC)=NC=N2)C=CC=C1)NC
Molecular Formula
C20H22N6O4
Molecular Weight
410.43
References & Citations
[1]Pascal Dao, et al. Inhibition of both focal adhesion kinase and fibroblast growth factor receptor 2 pathways induces anti-tumor and anti-angiogenic activities. Cancer Lett. 2014 Jun 28;348 (1-2) :88-99.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19199794-01PHM16

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