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Recombinant Human CD8A Protein, C-His

CAT: 1676-PR02894Size: 10μg/50μg/500μg/1mgDry Ice: NoHazardous: No
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CAT#:1676-PR02894Size:10μg/50μg/500μg/1mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD8 is a heterodimeric membrane glycoprotein on MHC class I-restricted T lymphocytes that cooperates with the alpha beta CD3 TCR in the recognition of MHC class I molecules presenting antigenic peptides. Cell surface CD8 molecules exist as either alpha/alpha homodimers or alpha/beta heterodimers, and most CD8+ T cells that undergo differentiation in the thymus express alpha/beta heterodimers. The CD8 b chain appears to be important for the thymic maturation of CD8+ T cells, because the number of mature CD8 single-positive T cells is decreased in CD8b gene-disrupted mice and most CD8+ T cells among gut intraepithelial lymphocytes in thymectomized mice express CD8 alpha/alpha homodimers.
Product Name Alternative
CD8A&CD8B; CD8 alpha&beta
Accession Number
P01732-1 & P10966-1
Tag
C-6His
Source
HEK293 Cells
Endotoxin
<1 EU/μg as determined by LAL test.
Purity
>95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 μg/mL.
Molecular Weight
22.7 & 21.0 kDa
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Protein Length
Ser22-Asp182 & Leu22-Pro170
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH7.4.
Species
Human

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