Products for Research Use Only
RegisterLogin

Recombinant Human Protein C

CAT: 1676-PR02883Size: 10μg/ 50μg/ 500μg/ 1mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1676-PR02883Size:10μg/ 50μg/ 500μg/ 1mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Protein C is a vitamin K-dependent plasma protein zymogen whose genetic mild or severe deficiencies are linked with risk for venous thrombosis or neonatal purpura fulminans, respectively. Studies over past decades showed that activated protein C (APC) inactivates factors (F) Va and VIIIa to down-regulate thrombin generation. More recent basic and preclinical research on APC has characterized the direct cytoprotective effects of APC that involve gene expression profile alterations, anti-inflammatory and anti-apoptotic activities and endothelial barrier stabilization. Activated protein C (APC) is generated from the protein C zymogen by proteolytic activation by thrombin, notably, APC, designated autoprothrombin II-A where ‘A’ indicated anticoagulant, had been studied by Seegers and colleagues, who thought it was a derivative of prothrombin.
Product Name Alternative
Coagulation Factor XIV; Protein C
Accession Number
P04070
Tag
C-6His
Source
HEK293 Cells
Endotoxin
<1 EU/μg as determined by LAL test.
Purity
>95% as determined by reducing SDS-PAGE.
Form
Liquid
Molecular Weight
51.1kDa
Shipping Conditions
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Protein Length
Thr19-Pro461
Formulation
Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, pH7.4.
Species
Human

Related Products

CatalogName
PR02884Recombinant Human Activated Protein C
PR15319Recombinant Human IL23 Protein, C-His & C-Strep
PR06174Recombinant Human IL23 Protein, C-His & C-Flag
PR09909Recombinant Human RET/c-RET Protein, C-His
PR16076Recombinant Human HDAC2 protein, C-6His & C-Flag
PR01242Recombinant Human FSH Protein, C-Flag & C-His
PR16086Recombinant Human HSP90α protein, C-6His
PR16170Recombinant Human OX40 protein, C-6His
PR16184Recombinant Human PD1 protein, C-Fc
PR16193Recombinant Human PDL1 protein, C-6His

Alternative Products

CatalogName
ARP2794-01Recombinant Human Leptin Human Recombinant Protein
MBS1561940-01Recombinant Human WAS protein
PPT-16033Human WAS Recombinant Protein
TP727635Human Recombinant Protein

Popular Products