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Glucosamine

CAT: 0804-HY-B1125-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1125-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
CAS Number
3416-24-8
Product Name Alternative
D-Glucosamine; Chitosamine
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; CFTR; Endogenous Metabolite; HIF/HIF Prolyl-Hydroxylase; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Autophagy; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Glucosamine.html
Purity
98.0
Solubility
DMSO : 3.33 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C[C@H](N)[C@H]([C@@H]([C@@H](CO)O)O)O
Molecular Formula
C6H13NO5
Molecular Weight
179.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Bruyère O, et al. Efficacy and safety of glucosamine sulfate in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016 Feb;45 (4 Suppl) :S12-7.|[2]Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38 (1) :212-9.|[3]Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells. Int J Oncol. 2014 May;44 (5) :1699-706.|[4]Park J, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl) . 2013 Nov;91 (11) :1273-84.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite
Citation 01
Am J Physiol Gastrointest Liver Physiol. 2025 Jun 1;328 (6) :G746-G759.|Biocell. 2025 Sep 25;49 (9) :1711-1731.|Cell Rep. 2025 Sep 10;44 (9) :116249.|Int Immunopharmacol. 2024 Oct 18;143 (Pt 2) :113427.|Microbiome. 2019 Mar 20;7 (1) :43. |Mil Med Res. 2025 Jul 28;12 (1) :39.|Nature. 2025 Jul;643 (8070) :192-200.|Theranostics. 2021 Mar 24;11 (12) :5650-5674.|Diabet Metab Synd Ob. 2025 Jul 28.|Laurea Magistrale in Biomedical Engineering, Politecnico di Milano. 2019 Jun.

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