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Clionamine B

CAT: 0804-HY-N10305Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10305Size:1 Each
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Description
Clionamine B is an autophagy stimulating aminosteroid isolated from the sponge Cliona celata. Clionamine B strongly stimulates autophagy in human breast cancer MCF-7 cells[1].
CAS Number
1042138-28-2
UNSPSC
12352005
Target
Autophagy
Type
Natural Products
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/clionamine-b.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3([H])[C@](OC([C@]3(O)CCCC(C)C)=O)([H])C[C@@]1([H])[C@@]4([H])[C@]([C@@]5([C@@](C[C@H](CC5)N)([H])CC4)C)([H])CC2
Molecular Formula
C27H45NO3
Molecular Weight
431.65
References & Citations
[1] Forestieri R, et al. Synthesis of clionamine B, an autophagy stimulating aminosteroid isolated from the sponge Cliona celata. Org Lett. 2013;15 (15) :3918-3921.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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