Products for Research Use Only
RegisterLogin

Recombinant Mouse IL4 Protein

CAT: 1676-PR00205Size: 10μg/50μg/500μg/1mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1676-PR00205Size:10μg/50μg/500μg/1mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Mouse Interleukin-4 (IL-4) is a monomeric, Th2 cytokine that shows pleiotropic effects during immune responses. It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four α­helix structure. IL­4 exerts its effects through two receptor complexes, Participates in at least several B-cell activation processes as well as of other cell types. IL­4 is primarily expressed by Th2­biased CD4+T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG1 and IgE in mouse B cells, acquisition of the Th2 phenotype by naïve CD4+T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL­4 plays a dominant role in the development of allergic inflammation and asthma. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
Product Name Alternative
Interleukin-4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; IGG1 induction factor; Lymphocyte stimulatory factor 1; IL-4; BSF-1
Accession Number
P07750
Tag
Tag free
Source
E.coli
Endotoxin
<1 EU/μg as determined by LAL test.
Purity
>95% as determined by SDS-PAGE.
Form
Lyophilized
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 μg/mL.
Molecular Weight
13.4 KDa
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Protein Length
His23-Ser140
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB,5% Sucrose,4% Mannitol,0.1% PS-80, pH 6.5.
Species
Mouse

Related Products

CatalogName
PR00267Recombinant Human IL4 Protein
PR00029Recombinant Human IL4 Protein, E. coli
PR00276Recombinant Human IL4 Protein, C-His
PR17215Recombinant Human IL4 Protein, C-His
PR06984Recombinant Human IL4 Protein, N-Fc
PR09996Recombinant Dog IL4 Protein, N-His
PR17074Recombinant Cynomolgus IL4 Protein, C-His
PR08424Recombinant Human IL4 Protein, C-His
PR09148Recombinant Dog IL4 Protein, C-Fc
PR09995Recombinant Dog IL4 Protein, C-His

Alternative Products

CatalogName
TP727653Mouse Recombinant Protein
RPM-236RECOMBINANT MOUSE PROTEIN

Popular Products