Products for Research Use Only
RegisterLogin

Volinanserin

CAT: 0804-HY-14940-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14940-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity.
CAS Number
139290-65-6
Product Name Alternative
MDL100907; M 100907
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Volinanserin.html
Purity
99.76
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
FC1=CC=C(CCN2CCC([C@@]([H])(O)C3=CC=CC(OC)=C3OC)CC2)C=C1
Molecular Formula
C22H28FNO3
Molecular Weight
373.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Sorensen SM, et al. Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. J Pharmacol Exp Ther. 1993 Aug;266 (2) :684-91.|[2]Ardayfio PA, et al. The 5-hydroxytryptamine2A receptor antagonist R- (+) -alpha- (2,3-dimethoxyphenyl) -1-[2- (4-fluorophenyl) ethyl-4-piperidinemethanol (M100907) attenuates impulsivity after both drug-induced disruption (dizocilpine) and enhancement (antidepressant drugs) of differential-reinforcement-of-low-rate 72-s behavior in the rat. J Pharmacol Exp Ther. 2008 Dec;327 (3) :891-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
5-HT1 Receptor; α-1 microglobulin

Alternative Products

CatalogName
S0313-25mgVolinanserin
A17115-50Volinanserin 50mg
A17115-25Volinanserin 25mg
A17115-200Volinanserin 200mg
A17115-100Volinanserin 100mg
A17115-10Volinanserin 10mg
A17115-5Volinanserin 5mg
AR-V06890-01Volinanserin HCl
AR-V06892-01Volinanserin-d4 HCl
022855Volinanserin Hydrochloride Salt

Popular Products